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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q92890
USC-OGP 2-DE database
:
Q92890
Q92890
General information about the entry
View entry in simple text format
Entry name
UFD1_HUMAN
Primary accession number
Q92890
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Ubiquitin fusion degradation protein 1 homolog; Short=UB fusion protein 1;.
Gene name
Name=UFD1L
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-5
{PLATELET 4-5}
Homo sapiens (Human)
map experimental info
PLATELET_4-5
MAP LOCATIONS:
SPOT OGP-0185
:
pI=4.70; Mw=26241
Cross-references
UniProtKB/Swiss-Prot
Q92890; UFD1_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
UFD1_HUMAN
Primary accession number
Q92890
Secondary accession number(s)
A8MW31 Q9Y5N0
Sequence was last modified on
November 13, 2007 (version 3)
Annotations were last modified on
March 15, 2017 (version 144)
Name and origin of the protein
Description
RecName: Full=Ubiquitin fusion degradation protein 1 homolog; Short=UB fusion protein 1;
Gene name
Name=UFD1L
Encoded on
Name=UFD1L
Keywords
3D-structure
;
Acetylation
;
Alternative splicing
;
Complete proteome
;
Cytoplasm
;
Nucleus
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
Ubl conjugation pathway
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
U64444; AAD08720.1
; -; mRNA
EMBL
AF141201; AAD28788.1
; -; mRNA
EMBL
CR456607; CAG30493.1
; -; mRNA
EMBL
AK225877; -
; NOT_ANNOTATED_CDS; mRNA
EMBL
AC000068; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
AC000087; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
BC001049; AAH01049.1
; -; mRNA
EMBL
BC005087; AAH05087.1
; -; mRNA
CCDS
CCDS13761.1; -. [Q92890-2]
; .
CCDS
CCDS33600.2; -. [Q92890-3]
; .
RefSeq
NP_001030324.2; NM_001035247.2. [Q92890-3]
; .
RefSeq
NP_005650.2; NM_005659.6. [Q92890-2]
; .
UniGene
Hs.474213; -
; .
PDB
2YUJ; NMR
; -; A=11-193
PDB
5C1B; X-ray
; 3.08 A; U/V=221-241
PDBsum
2YUJ; -
; .
PDBsum
5C1B; -
; .
ProteinModelPortal
Q92890; -
; .
SMR
Q92890; -
; .
BioGrid
113200; 96
; .
DIP
DIP-45954N; -
; .
IntAct
Q92890; 32
; .
MINT
MINT-2837704; -
; .
STRING
9606.ENSP00000263202; -
; .
iPTMnet
Q92890; -
; .
PhosphoSitePlus
Q92890; -
; .
BioMuta
UFD1L; -
; .
DMDM
160332310; -
; .
OGP
Q92890; -
; .
EPD
Q92890; -
; .
PaxDb
Q92890; -
; .
PeptideAtlas
Q92890; -
; .
PRIDE
Q92890; -
; .
DNASU
7353; -
; .
Ensembl
ENST00000263202; ENSP00000263202
; ENSG00000070010. [Q92890-2]; .
Ensembl
ENST00000399523; ENSP00000382439
; ENSG00000070010. [Q92890-3]; .
GeneID
7353; -
; .
KEGG
hsa:7353; -
; .
UCSC
uc002zpm.3; human. [Q92890-2]
; .
CTD
7353; -
; .
DisGeNET
7353; -
; .
GeneCards
UFD1L; -
; .
HGNC
HGNC:12520; UFD1L
; .
HPA
HPA030287; -
; .
HPA
HPA030288; -
; .
HPA
HPA073425; -
; .
MalaCards
UFD1L; -
; .
MIM
601754; gene
; .
neXtProt
NX_Q92890; -
; .
OpenTargets
ENSG00000070010; -
; .
Orphanet
567; 22q11.2 deletion syndrome
; .
PharmGKB
PA37167; -
; .
eggNOG
KOG1816; Eukaryota
; .
eggNOG
COG5140; LUCA
; .
GeneTree
ENSGT00390000002408; -
; .
HOGENOM
HOG000212737; -
; .
HOVERGEN
HBG001266; -
; .
InParanoid
Q92890; -
; .
KO
K14016; -
; .
OMA
ADHSSYA; -
; .
OrthoDB
EOG091G0KO7; -
; .
PhylomeDB
Q92890; -
; .
TreeFam
TF314581; -
; .
Reactome
R-HSA-110320; Translesion Synthesis by POLH
; .
Reactome
R-HSA-5689880; Ub-specific processing proteases
; .
UniPathway
UPA00144; -
; .
ChiTaRS
UFD1L; human
; .
EvolutionaryTrace
Q92890; -
; .
GeneWiki
UFD1L; -
; .
GenomeRNAi
7353; -
; .
PRO
PR:Q92890; -
; .
Proteomes
UP000005640; Chromosome 22
; .
Bgee
ENSG00000070010; -
; .
CleanEx
HS_UFD1L; -
; .
ExpressionAtlas
Q92890; baseline and differential
; .
Genevisible
Q92890; HS
; .
GO
GO:0005829; C:cytosol
; IEA:UniProtKB-SubCell; .
GO
GO:0005783; C:endoplasmic reticulum
; IDA:HPA; .
GO
GO:0005654; C:nucleoplasm
; TAS:Reactome; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0036501; C:UFD1-NPL4 complex
; IPI:ParkinsonsUK-UCL; .
GO
GO:0034098; C:VCP-NPL4-UFD1 AAA ATPase complex
; IDA:UniProtKB; .
GO
GO:0004843; F:thiol-dependent ubiquitin-specific protease activity
; TAS:ProtInc; .
GO
GO:0071712; P:ER-associated misfolded protein catabolic process
; IMP:ParkinsonsUK-UCL; .
GO
GO:0070987; P:error-free translesion synthesis
; TAS:Reactome; .
GO
GO:0039536; P:negative regulation of RIG-I signaling pathway
; IMP:UniProtKB; .
GO
GO:0032480; P:negative regulation of type I interferon production
; IMP:UniProtKB; .
GO
GO:0016579; P:protein deubiquitination
; TAS:Reactome; .
GO
GO:0030970; P:retrograde protein transport
; ER to cytosol; IMP:ParkinsonsUK-UCL
GO
GO:0001501; P:skeletal system development
; TAS:ProtInc; .
GO
GO:0006511; P:ubiquitin-dependent protein catabolic process
; IMP:UniProtKB; .
InterPro
IPR004854; UFD1
; .
PANTHER
PTHR12555; PTHR12555
; 1; .
Pfam
PF03152; UFD1
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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